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Indeed, a growing body of evidence supports the concept that initiation of treatment with disease modifying anti-IBD drugs (DMAID) during the window of opportunity of early-stage CD (up to approximately 18 months from diagnosis) may change the natural progression of the disease

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Prochlorperazine exerts antiemetic effects and was shown to inhibit apomorphine-induced vomiting by blocking D2 dopamine receptors in the CTZ